Material Safety Data Sheet: 2-Methyl-1,3-Propanediol (MPO)

Identification

Product Name: 2-Methyl-1,3-Propanediol
Chemical Formula: C4H10O2
Synonyms: MPO, 2-Methylpropane-1,3-diol
CAS Number: 2163-42-0
Recommended Use: Industrial applications, intermediates in polymer production
Manufacturer/Supplier: Relevant chemical supply or manufacturing company
Contact Information: Address, emergency telephone number, email for product safety support

Hazard Identification

Classification: Not classified as hazardous according to GHS criteria
Signal Word: Not required
Hazard Statements: May cause mild skin and eye irritation. Inhalation of vapors or mists at high concentrations may cause dizziness or respiratory discomfort.
Precautionary Statements: Avoid breathing dust/fume/gas/mist/vapors/spray. Use personal protective equipment if exposure risk exists.
Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
Symptoms: Redness, irritation, possible headache or nausea if inhaled in poorly ventilated areas

Composition / Information on Ingredients

Chemical Name: 2-Methyl-1,3-Propanediol
Content: ≥99%
Impurities: Trace amounts of related diols or residual starting materials below 1% combined
Additives or Stabilizers: None noted for technical product

First Aid Measures

Inhalation: Move to fresh air, provide oxygen if breathing is difficult, seek medical attention if symptoms persist
Skin Contact: Wash skin thoroughly with plenty of soap and water. Remove contaminated clothing and launder before reuse.
Eye Contact: Rinse immediately with plenty of water for at least 15 minutes. Remove contact lenses if present and easy to do. Seek medical attention if irritation persists.
Ingestion: Rinse mouth with water. Do not induce vomiting. Seek medical advice if large quantities are ingested or symptoms occur.
Indication of Immediate Medical Attention Needed: Prolonged symptoms or significant exposure by any route

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, carbon dioxide, dry chemical powder, alcohol-resistant foam
Unsuitable Extinguishing Methods: Strong water jets may spread the product
Specific Hazards: Burns may produce toxic fumes including carbon monoxide and carbon dioxide
Protective Equipment for Firefighters: Self-contained breathing apparatus and full protective gear recommended
Special Firefighting Procedures: Remove containers from path of fire if safe. Cool nearby containers with water spray.

Accidental Release Measures

Personal Precautions: Use appropriate personal protective equipment to avoid skin, eye, or respiratory contact
Environmental Precautions: Prevent further leakage or spillage if safe. Avoid release into drains, soil, or waterways
Clean-Up Methods: Absorb spilled liquid with inert material such as sand or earth. Sweep up and place in a suitable container for disposal.
Decontamination: Wash area with water and detergent after material is removed
Emergency Procedures: Ventilate the area. Notify proper authorities if large spill enters environment.

Handling and Storage

Safe Handling: Avoid contact with skin, eyes, and clothing. Use in well-ventilated areas. Do not inhale vapor or mist.
Storage Conditions: Store in a cool, dry, well-ventilated place away from incompatible substances such as strong oxidizers
Container Requirements: Keep container tightly closed and clearly labeled. Use only corrosion-resistant materials for storage.
Other Precautions: Maintain good housekeeping to prevent accidental spills and exposure

Exposure Controls and Personal Protection

Occupational Exposure Limits: No specific OEL has been established
Engineering Controls: Use local exhaust ventilation to minimize vapor concentration
Personal Protective Equipment: Gloves: Chemical-resistant recommended
Eyes: Safety goggles or face shield
Respiratory: NIOSH-approved respirator based on risk assessment for airborne concentrations
Protective Clothing: Chemical-resistant apron or lab coat
Hygiene Measures: Wash hands thoroughly after handling. Remove contaminated clothing and wash before reuse.

Physical and Chemical Properties

Appearance: Clear, colorless viscous liquid
Odor: Mild, slightly sweet
Odor Threshold: Not available
pH: Approx. 6-8 at 20°C in water
Melting Point/Freezing Point: -54°C
Boiling Point: 212-214°C at 101.3 kPa
Flash Point: 126°C (Closed cup)
Evaporation Rate: Not determined
Flammability: Not classified as flammable under current regulations
Vapor Pressure: 0.02 mmHg at 20°C
Solubility: Miscible in water
Partition Coefficient (n-octanol/water): Log Pow estimated at -0.92
Auto-ignition Temperature: 378°C
Decomposition Temperature: No data available
Viscosity: 45 mPa·s at 25°C
Molecular Weight: 90.12 g/mol

Stability and Reactivity

Reactivity: Stable under normal storage and handling conditions
Chemical Stability: Stable, not sensitive under recommended conditions
Hazardous Reactions: No dangerous reactions known under normal use
Incompatible Materials: Strong oxidizers, strong acids, acid chlorides
Hazardous Decomposition Products: Thermal decomposition may release toxic gases such as carbon monoxide and carbon dioxide
Conditions to Avoid: Excessive heat, ignition sources, contact with incompatible substances

Toxicological Information

Acute Toxicity: LD50 (oral, rat): >2,000 mg/kg; LD50 (dermal, rabbit): >2,000 mg/kg
Skin Irritation: Mild irritation possible
Eye Irritation: Mild to moderate irritation noted in some animal studies
Respiratory Sensitization: Not classified as a respiratory sensitizer
Skin Sensitization: Not a known skin sensitizer
Mutagenicity: No mutagenic effects detected in tested bacterial or mammalian cell systems
Carcinogenicity: No information suggesting carcinogenic effects in humans
Reproductive Toxicity: No reproductive or developmental toxicity observed in animal studies
Other Information: Repeated or prolonged exposure may lead to skin dryness or cracking

Ecological Information

Ecotoxicity: Fish (96 h LC50): >100 mg/l (low aquatic toxicity); Daphnia (48 h EC50): >100 mg/l; Algae (72 h EC50): >100 mg/l
Persistence and Degradability: Readily biodegradable in water (based on available data)
Bioaccumulative Potential: Low (Log Pow below 1)
Mobility in Soil: High mobility likely, soluble in water
Other Adverse Effects: No significant adverse environmental effects documented under normal use

Disposal Considerations

Waste Disposal Methods: Dispose in accordance with local, regional, and national regulations. Incineration or landfill by licensed contractor recommended for large quantities.
Contaminated Packaging: Dispose of as unused product. Containers should be triple-rinsed before recycling or disposal.
Environmental Precautions: Prevent spillage from entering soil, waterways, or sewers to minimize environmental impact
Special Notes: Waste management should align with safe handling and environmental protection practices.

Transport Information

UN Number: Not regulated as dangerous goods
Proper Shipping Name: 2-Methyl-1,3-Propanediol
Transport Hazard Class: Not applicable
Packing Group: Not regulated
Marine Pollutant: No
Special Transport Precautions: Ensure containers are secured and properly labeled during transit. Protect from direct sunlight and excessive heat.

Regulatory Information

Inventory Status: Listed on TSCA (US), EINECS/ELINCS (EU), DSL (Canada), ENCS (Japan), and other relevant inventories
Labeling Requirements: No special hazard labeling needed under GHS criteria
OSHA Hazard Communication: Not classified as hazardous
SARA Title III: Not listed as an extremely hazardous substance
REACH Status (Europe): Registration/notification in compliance with REACH may be required for specific applications
Other Regulations: Observe all applicable federal, state, and local regulations related to chemical handling and worker safety. Regularly update according to changes in chemical legislation.