MSDS for Bisphenol A (BPA)

Identification

Product Name: Bisphenol A
CAS Number: 80-05-7
Chemical Formula: C₁₅H₁₆O₂
Synonyms: Diphenylolpropane, 4,4'-Isopropylidenediphenol
Use: Production of polycarbonate plastics, epoxy resins, thermal paper, adhesives, and coatings
Manufacturer/Distributor: Information varies by supplier
Emergency Contact: Refer to supplier’s emergency hotline or national chemical emergency number

Hazard Identification

Classification: Eye irritation (Category 2A), Skin sensitizer (Category 1), Reproductive toxicity (Category 2), Specific target organ toxicity - repeated exposure (Category 2)
Signal Word: Warning
Hazard Statements: Causes serious eye irritation, may cause an allergic skin reaction, may damage fertility or the unborn child, may cause damage to organs through prolonged or repeated exposure
Symbols: Exclamation mark, Health hazard
Route of Exposure: Inhalation, skin and eye contact, ingestion
Symptoms: Irritation of skin, eyes, respiratory tract, possible reproductive and developmental effects from long-term exposure

Composition / Information on Ingredients

Chemical Name: Bisphenol A
Concentration: ≥ 99%
Impurities: Trace phenols, residual isopropylidenebis(phenol) derivates depending on manufacturer
CAS Number: 80-05-7
Other Ingredients: None significant reported in commercial formulations

First Aid Measures

Inhalation: Move to fresh air, keep patient comfortable, administer artificial respiration if breathing is difficult, seek immediate medical attention
Skin Contact: Take off contaminated clothing, wash skin with plenty of soap and water for at least 15 minutes, consult physician if irritation persists
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present and easy to do, continue rinsing, get medical aid
Ingestion: Rinse mouth, do not induce vomiting, drink water if conscious, seek medical attention
Notes for Medical Staff: Treat symptoms, ensure airway and breathing are secure, no specific antidote

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, foam, dry chemical, carbon dioxide
Hazards from Combustion: Toxic fumes of carbon monoxide, carbon dioxide, phenolic compounds
Special Protective Equipment: Firefighters must wear full protective clothing and self-contained breathing apparatus
Advice for Firefighters: Use water spray to cool containers, avoid breathing fumes, evacuate area if needed, contain water runoff

Accidental Release Measures

Personal Precautions: Wear suitable protective clothing, gloves, eye and face protection, avoid dust formation
Environmental Precautions: Prevent entry into sewers, waterways, or soil, inform authorities if significant release occurs
Methods for Clean-Up: Collect spilled material mechanically, sweep or scoop up and place in suitable container for disposal, ventilate affected area, wash spill site after material clean-up completed
Precautions for Safe Handling During Clean-Up: Avoid creating dust, ensure adequate ventilation, do not touch or walk through spilled material

Handling and Storage

Precautions for Handling: Avoid contact with skin, eyes, and clothing, avoid inhaling dust or vapors, wash thoroughly after handling, do not eat, drink, or smoke while using product
Conditions for Safe Storage: Store in tightly closed container in a cool, dry, well-ventilated place, keep away from incompatible materials such as strong oxidizers and acids, protect from sunlight and moisture, maintain temperature below 30°C
Incompatible Materials: Strong oxidizing agents, strong acids, bases, some plastics
Packaging Materials: Use containers resistant to organic chemicals, prevent leakage

Exposure Controls and Personal Protection

Occupational Exposure Limits: OSHA PEL: Not established; ACGIH TLV: Not established; Manufacturer recommended limit: 5 mg/m³ TWA
Engineering Controls: Use local exhaust ventilation, maintain adequate general ventilation to control exposure
Personal Protective Equipment:

• Eye Protection: Chemical safety goggles or face shield
• Skin Protection: Protective gloves made of nitrile rubber, neoprene or PVC, protective clothing to prevent contact
• Respiratory Protection: NIOSH-approved respirator if dust or vapors are generated above recommended levels
• Hygiene Measures: Wash hands after handling, do not reuse contaminated clothing, promptly remove contaminated clothing and wash before reuse

Physical and Chemical Properties

Appearance: White to off-white flakes or powder
Odor: Mild, phenolic
Odor Threshold: Not determined
pH: Not applicable (insoluble in water), 8-10 in aqueous suspension
Melting Point/Freezing Point: 155°C
Boiling Point/Range: Decomposes before boiling
Flash Point: 252°C (closed cup)
Evaporation Rate: Not applicable
Flammability: Not highly flammable, dust may form explosive mixture
Vapor Pressure: 5 x 10^-6 mmHg at 25°C
Vapor Density: Not applicable
Relative Density: 1.20 (water = 1)
Solubility: Very slightly soluble in water (<0.3 mg/L at 25°C), soluble in organic solvents such as acetone, methanol, ether
Partition Coefficient (log Kow): 3.32
Auto-Ignition Temperature: 460°C
Decomposition Temperature: >220°C
Viscosity: Not relevant (solid)

Stability and Reactivity

Chemical Stability: Stable under recommended handling and storage conditions
Possibility of Hazardous Reactions: Polymerization will not occur under normal conditions, may react with strong acids and oxidizers
Conditions to Avoid: High temperatures, open flames, moisture, incompatible chemicals
Incompatible Materials: Strong oxidizing agents, strong acids and bases, chlorinating agents
Hazardous Decomposition Products: Phenol, carbon monoxide, carbon dioxide, other organic compounds

Toxicological Information

Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Toxicity: LD₅₀ oral (rat): 3250 mg/kg; LD₅₀ dermal (rabbit): >3000 mg/kg
Chronic Toxicity: Possible reproductive toxicity; some animal studies link long-term exposure to hormone disruption, developmental effects, increased risk of certain cancers
Irritation/Corrosivity: Causes skin and eye irritation
Allergic Sensitization: May cause allergic skin reaction
Carcinogenicity: Not classified as carcinogenic by IARC, NTP, or OSHA, but classified as toxic to reproduction by EU
Mutagenicity: Not found to be mutagenic in standard test systems
Other Effects: Endocrine-disrupting activity has been widely reported in peer-reviewed studies

Ecological Information

Aquatic Toxicity: Toxic to aquatic organisms (fish, daphnia, algae), acute LC₅₀ (fish, 96h): 4.6 mg/L
Persistence and Degradability: Not readily biodegradable, persists in environment for extended periods
Bioaccumulation: Potential for bioaccumulation exists, moderate log Kow suggests tendency to concentrate in organisms
Soil Mobility: Low mobility in soil due to low water solubility, tends to bind to sediments and organic matter
Other Adverse Effects: Endocrine-disrupting effects observed in aquatic species, may affect hormone balance in wildlife

Disposal Considerations

Waste Disposal Methods: Dispose of in accordance with federal, state, and local regulations, incineration preferred for large quantities, do not discharge into drains or open water
Container Disposal: Triple rinse empty containers, dispose as hazardous waste, do not reuse containers
Precautions: Prevent contamination of soil, water, and drains during disposal, ensure proper handling by licensed disposal contractor

Transport Information

UN Number: Not regulated for ground or air transport as a hazardous substance
UN Proper Shipping Name: Bisphenol A
Transport Hazard Class: Not classified
Packing Group: Not assigned
Environmental Hazards: Marine pollutant if shipped in bulk, contain leak during transport
Special Precautions: Protect from physical damage, avoid exposure to moisture and extreme temperature during transportation

Regulatory Information

OSHA: Not specifically regulated
TSCA: Listed
REACH: Registered, classified as a substance of very high concern (SVHC) for endocrine-disrupting properties
EU Classification: Repr. 1B, Skin Sens. 1, Eye Irrit. 2
Canadian WHMIS: D2A, D2B
California Proposition 65: Listed as a chemical known to cause reproductive toxicity
Other Regulations: Subject to community right-to-know laws and environmental protection regulations in multiple jurisdictions