Cyclohexane Material Safety Data Sheet (MSDS)

Identification

Product Name: Cyclohexane
Chemical Formula: C6H12
Other Names: Hexahydrobenzene, Hexamethylene
Recommended Use: Solvent, chemical intermediate
Manufacturer/Supplier: [Manufacturer information]
Emergency Phone: [Emergency contact number]
CAS Number: 110-82-7
UN Number: UN1145

Hazard Identification

Classification: Flammable liquid (Category 2), Acute toxicity (Category 4, oral and inhalation), Skin irritation (Category 2), Specific target organ toxicity (single exposure, Category 3), Aspiration hazard (Category 1)
Label Elements: Flame, Exclamation mark, Health hazard
Signal Word: Danger
Hazard Statements: Highly flammable liquid and vapor. May be fatal if swallowed and enters airways. Causes skin irritation. May cause drowsiness or dizziness. Harmful if inhaled. Toxic to aquatic life with long lasting effects.
Precautionary Statements: Keep away from heat, sparks, open flames, and hot surfaces. Use explosion-proof equipment. Avoid breathing vapor or mist. Wash exposed skin thoroughly after handling. Use only outdoors or in well-ventilated area. Avoid release to the environment. Wear protective gloves, eye/face protection, and protective clothing.

Composition / Information on Ingredients

Cyclohexane Content: 99.5% or higher
Chemical Name: Cyclohexane
CAS Registry Number: 110-82-7
Impurities: May contain trace levels of benzene or methylcyclopentane depending on source
Molecular Weight: 84.16 g/mol

First Aid Measures

Inhalation: Move exposed person to fresh air immediately. If breathing is labored, administer oxygen by qualified personnel. Call a physician if symptoms develop.
Skin Contact: Remove contaminated clothing. Wash affected skin with plenty of soap and water for at least 15 minutes. Seek medical attention if skin irritation or other effects persist.
Eye Contact: Rinse opened eye with running water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. Get medical aid if irritation occurs.
Ingestion: Do not induce vomiting to avoid aspiration hazard. Call physician immediately. If victim is conscious, rinse mouth and give small quantities of water.
Important Symptoms: Headache, dizziness, nausea, respiratory irritation, drowsiness, dry skin

Fire-Fighting Measures

Suitable Extinguishing Media: Use dry chemical, foam, or carbon dioxide. Water spray can be used to cool fire-exposed containers.
Unsuitable Media: Water jets may spread fire.
Fire Hazards: Extremely flammable liquid and vapor. Vapors may form explosive mixtures with air. Flashback along vapor trail possible.
Specific Hazards: Decomposition may produce carbon monoxide, carbon dioxide, irritating vapors.
Protective Equipment: Wear fire-resistant protective clothing and self-contained breathing apparatus.
Additional Advice: Evacuate area. Prevent runoff to sewers or waterways.

Accidental Release Measures

Personal Precautions: Eliminate all ignition sources. Ventilate area. Wear full protective equipment, including respiratory protection.
Environmental Precautions: Prevent entry into drains, waterways, and soil. Notify authorities if contamination occurs.
Clean-Up Methods: Contain and absorb spill with non-combustible materials (sand, earth, vermiculite). Collect and place in a labeled, closed container for proper disposal.
Decontamination: Wash spill area with soap and water after material removal.
Special Instructions: Use nonsparking tools and equipment.

Handling and Storage

Handling: Avoid inhalation, ingestion, and contact with skin, eyes, or clothing. Keep away from ignition sources including static discharge. Use only in well-ventilated areas.
General Hygiene: Wash hands thoroughly after handling and before eating, drinking, or smoking.
Storage: Store tightly closed in a cool, dry, well-ventilated area away from incompatible materials (strong oxidizers, acids). Use grounded containers and explosion-proof equipment.
Incompatible Materials: Keep away from strong oxidizing agents, strong acids.
Storage Conditions: Keep container tightly closed and away from heat, sources of ignition, and direct sunlight.
Special Precautions: Keep containers upright. Label containers clearly.

Exposure Controls and Personal Protection

Exposure Limits: OSHA PEL: 300 ppm (1050 mg/m³) TWA; ACGIH TLV: 100 ppm TWA
Engineering Controls: Provide adequate ventilation, preferably local exhaust at points of emission. Use explosion-proof ventilation.
Personal Protective Equipment: Eye/Face Protection: Chemical safety goggles
Skin Protection: Chemical-resistant gloves (such as nitrile), lab coat or apron
Respiratory Protection: Organic vapor respirator if ventilation is not adequate
Other Protection: Emergency eye wash and safety shower accessible
Hygiene Measures: Do not eat, drink, or smoke during use. Remove contaminated clothing and wash before reuse.

Physical and Chemical Properties

Appearance: Clear, colorless liquid
Odor: Sweet, pungent, gasoline-like
Odor Threshold: 25-300 ppm
pH: Not applicable
Melting Point: 6.5°C
Boiling Point: 80.7°C
Flash Point: -20°C (closed cup)
Evaporation Rate: 1.2 (n-butyl acetate = 1)
Flammability: Extremely flammable
Vapor Pressure: 97 mmHg (20°C)
Vapor Density: 2.98 (air = 1)
Specific Gravity: 0.78 (water = 1)
Solubility in Water: Insoluble
Partition Coefficient (log Kow): 3.44
Auto-ignition Temperature: 245°C
Decomposition Temperature: Data not available
Viscosity: 0.98 mPa.s (25°C)

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions. Volatile and flammable.
Possibility of Hazardous Reactions: May react violently with strong oxidizers (such as nitric acid, hydrogen peroxide).
Hazardous Polymerization: Does not polymerize.
Conditions to Avoid: Heat, sparks, open flames, static electricity, and incompatible materials.
Incompatible Materials: Strong oxidizing agents, strong acids.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, other unidentified decomposition products may be released in fire.

Toxicological Information

Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Toxicity: Oral LD50 (rat): 12705 mg/kg; Dermal LD50 (rabbit): >2000 mg/kg; Inhalation LC50 (rat, 4h): 13000 ppm
Skin Corrosion/Irritation: Causes irritation
Serious Eye Damage/Irritation: May cause mild to moderate irritation
Respiratory or Skin Sensitization: Not a known sensitizer
Germ Cell Mutagenicity: Not classified
Carcinogenicity: Not classified as carcinogenic by IARC, NTP, or OSHA
Reproductive Toxicity: No evidence of reproductive toxicity in animal studies
STOT-Single Exposure: May cause drowsiness, dizziness, and respiratory tract irritation
STOT-Repeated Exposure: No significant target organ effects reported from repeated exposures in animals
Aspiration Hazard: May be fatal if swallowed and enters airways
Other Effects: Central nervous system depression, including euphoria, headache, nausea, and at high concentrations, loss of consciousness

Ecological Information

Aquatic Toxicity: Harmful to aquatic life with long lasting effects. Fish (LC50, 96 hr): 23-75 mg/L (varies by species). Invertebrates (EC50, 48 hr, Daphnia): 0.9 mg/L.
Persistence and Degradability: Moderately persistent in the environment. Biodegradable under aerobic conditions, but evaporation from water and soil is likely.
Bioaccumulation Potential: High potential for bioaccumulation (log Kow 3.44). May concentrate in aquatic organisms.
Mobility in Soil: Low to moderate mobility due to volatility; may migrate to groundwater.
Other Adverse Effects: Ozone formation potential. Anoxic conditions can retard degradation.

Disposal Considerations

Waste Treatment Methods: Handle as a hazardous waste. Dispose via licensed hazardous waste contractor.
Disposal of Product: Incinerate or treat by chemical mean in accordance with local, regional, and national regulations. Avoid release to the environment.
Contaminated Packaging: Triple rinse. Containers must be thoroughly cleaned before reuse or recycling. Dispose of container as hazardous material.
Special Precautions: Do not allow material or rinsate to contaminate soil or waterways. Obtain permission from regulatory agencies for disposal.

Transport Information

UN Number: UN1145
UN Proper Shipping Name: Cyclohexane
Transport Hazard Class: 3 (Flammable liquid)
Packing Group: II
Hazard Labels: Flammable Liquid
Special Precautions for User: Keep away from heat and open flames. Avoid rough handling and impacts during transport.
Environmental Hazards: Marine pollutant. Notify carrier if transporting via water.
Bulk Transport: Follow requirements of MARPOL, IBC Code, and other shipping protocols as applicable.

Regulatory Information

TSCA Status: Listed in the US TSCA inventory
OSHA Hazard: Classified as hazardous according to OSHA (29 CFR 1910.1200)
SARA 313: Subject to reporting under Section 313
RCRA Status: Hazardous waste under RCRA (U056)
CERCLA Reportable Quantity: 1,000 lbs (454 kg)
California Proposition 65: Not listed
EINECS: 203-806-2
Other International Listings: Included in Canadian DSL, Japanese ENCS, and Australian AICS
Labeling According to Regulation (EC) No. 1272/2008 (CLP): GHS pictograms, hazard statements, and precautionary statements required