Material Safety Data Sheet: Piperazine 68% (PIP-68%)

Identification

Product Name: Piperazine 68%
Chemical Name: Piperazine Solution
Synonyms: Diethylenediamine solution
CAS Number: 110-85-0
Recommended Use: Used as a corrosion inhibitor, chemical intermediate, and in water treatment applications
Manufacturer: (Manufacturer contact info required)
Emergency Contact: (Emergency phone number required)

Hazard Identification

GHS Classification: Acute toxicity (Oral/Derma/Inhalation), Skin corrosion, Serious eye damage
Label Elements: Danger, Corrosive, Toxics
Hazard Statements: Causes severe skin burns and eye damage, Harmful if swallowed or inhaled, May cause respiratory irritation
Signal Word: Danger
Pictogram: Corrosive and exclamation mark symbols
Precautionary Statements: Avoid breathing vapors, wear protective clothing, wash hands thoroughly after handling, if in eyes rinse cautiously with water, seek medical attention if exposed or concerned

Composition / Information on Ingredients

Substance: Piperazine Solution
Chemical Formula: C4H10N2•xH2O
Concentration: 68% piperazine by weight
Impurities: Water and trace impurities from manufacturing
Additional Information: No additional hazardous components contributing over 1% by weight

First Aid Measures

Eye Contact: Rinse thoroughly for at least 15 minutes, remove contact lenses if present, seek immediate medical advice
Skin Contact: Remove contaminated clothing, rinse skin with water for several minutes, get medical attention if irritation or burns develop
Inhalation: Remove to fresh air, provide artificial respiration if needed, seek immediate medical attention
Ingestion: Do not induce vomiting, rinse mouth, give water to drink if victim is conscious, seek medical assistance right away
Most Important Symptoms: Burning sensation, coughing, shortness of breath, severe pain or irritation in affected areas

Fire-Fighting Measures

Extinguishing Media: Use alcohol-resistant foam, dry chemical, carbon dioxide, or water spray
Hazardous Combustion Products: Emits toxic fumes of nitrogen oxides and carbon oxides under fire conditions
Fire Fighting Instructions: Wear self-contained breathing apparatus and full protective clothing, approach from upwind, cool containers with water spray to prevent overheating
Special Hazards: Container rupture may occur due to buildup of pressure in heat exposure, avoid inhaling combustion products

Accidental Release Measures

Personal Precautions: Wear chemical protective gloves, eye protection, and respirator if vapors are present
Environmental Precautions: Prevent runoff to drains, surface water, or soil
Containment: Evacuate area, ventilate, and contain spill with inert absorbent material (e.g., sand or vermiculite)
Cleanup Methods: Collect and place in suitable, tightly closed chemical waste containers for disposal, wash area with water after cleanup is complete
Notification: Report large spills to appropriate environmental and regulatory authorities

Handling and Storage

Safe Handling: Work in well-ventilated areas, avoid breathing vapors, keep away from sources of ignition, prevent skin and eye contact, use only with proper chemical resistant gloves and goggles
Storage Conditions: Store in cool, dry, well-ventilated area in tightly closed containers, keep away from incompatible substances like acids, oxidizers, and moisture
Incompatibilities: Strong acids, strong oxidizing agents, nitrites
Specific Use: Restricted to trained personnel familiar with chemical safety protocols

Exposure Controls and Personal Protection

Occupational Exposure Limit: No established OSHA or ACGIH exposure limits for piperazine
Engineering Controls: Use fume hoods, local exhaust ventilation, and closed systems where practical
Respiratory Protection: NIOSH-approved respirators in aerosol-generating tasks or if concentration exceeds safe limits
Skin Protection: Use chemical-resistant gloves, long-sleeved clothing, and apron
Eye Protection: Tight-fitting chemical splash goggles and face shield
General Hygiene: Wash hands and face before meals or breaks, do not eat or drink in work area, remove contaminated clothing promptly

Physical and Chemical Properties

Appearance: Colorless to pale yellow aqueous solution
Odor: Ammonia-like, pungent
Melting Point: Not applicable (solution)
Boiling Point: Approximately 100°C (water-based solution)
pH: Strongly basic, typically 10-11
Vapor Pressure: 16 mmHg @ 25°C
Solubility: Completely miscible in water
Density: About 1.1 g/cm³
Viscosity: Moderate
Flash Point: Not flammable as aqueous solution
Auto Ignition Temperature: Not determined for solution
Decomposition Temperature: Above 200°C

Stability and Reactivity

Chemical Stability: Stable under normal storage and handling conditions
Reactivity: Reacts with acids to release heat and flammable gases
Possibility of Hazardous Reactions: Hazardous polymerization does not occur
Conditions to Avoid: Incompatible materials, excessive heat, contact with strong acids or oxidizers
Incompatible Materials: Acids, oxidizing agents
Hazardous Decomposition Products: Releases ammonia, nitrogen oxides, carbon oxides during thermal decomposition

Toxicological Information

Acute Toxicity: Harmful if swallowed, inhaled, or absorbed through skin
Oral LD₅₀ (Rat): ~2,800 mg/kg
Dermal LC₅₀ (Rabbit): ~8,660 mg/kg
Skin Irritation: Causes burns
Eye Damage: Severe, may result in permanent injury
Respiratory Effects: May cause cough, shortness of breath, respiratory tract irritation
Sensitization: Skin contact can sensitize in some workers
Chronic Effects: Prolonged exposure may damage liver, kidneys; some links to reproductive effects, mutations, tumors in animal studies
Carcinogenicity: Not classified as carcinogenic by IARC, NTP, or OSHA

Ecological Information

Aquatic Toxicity: Toxic to aquatic organisms, may cause long-term adverse effects
Persistence: Degrades moderately in the environment
Bioaccumulative Potential: Low, but mobile in aquatic systems
Mobility in Soil: Likely to migrate to groundwater in liquid form
Additional Data: Avoid release to environment, hazardous to fish and invertebrates at low concentrations

Disposal Considerations

Waste Treatment Methods: Dispose of in accordance with local, regional, national, and international regulations
Disposal of Product: Hazardous chemical waste, incineration preferred in a chemical disposal facility
Disposal of Containers: Rinse thoroughly before recycling or disposal; do not reuse for other chemicals
Additional Information: Notify relevant authorities if significant spills enter water or soil

Transport Information

UN Number: 2372 (Piperazine solution)
UN Proper Shipping Name: Piperazine, aqueous solution
Transport Hazard Class: 8 (Corrosive substance)
Packing Group: III
Marine Pollutant: Not designated as marine pollutant for most shipping modes
Special Precautions: Secure all containers, transport under proper temperature and protection from damage; drivers and handlers should wear protective equipment

Regulatory Information

EU Classification: Acute toxicity, corrosive (EC No. 203-808-3)
US TSCA: Listed
SARA Title III: Not listed as an Extremely Hazardous Substance; reportable quantity varies by region
Other Regulatory Info: Subject to workplace safety legislation, proper labeling and documentation required for storage and transport. Users must comply with all occupational health and environmental regulations.