Material Safety Data Sheet for Propyl Acetate

Identification

Product Name: Propyl Acetate
Chemical Formula: C5H10O2
Synonyms: n-Propyl acetate, 1-Acetoxypropane
CAS Number: 109-60-4
Recommended Use: Solvent for coatings, inks, adhesives, and cleaning agents
Manufacturer Contact: Refer to supplier information or safety officer for contact details
Emergency Contact Number: Provided by local regulatory guidelines or company emergency plan

Hazard Identification

Physical Hazards: Highly flammable liquid and vapor, can form explosive mixtures with air
Health Hazards: Irritates eyes, nose, throat, and skin, may cause drowsiness or dizziness, prolonged/excessive exposure damages the central nervous system
GHS Label Elements: Flame symbol, exclamation mark
Signal Word: Danger
Hazard Statements: H225 (Highly flammable), H319 (Causes serious eye irritation), H336 (May cause drowsiness or dizziness)
Precautionary Statements: Avoid heat, sparks, static discharge, use only outdoors or in well-ventilated areas, avoid breathing vapors, wear protective equipment

Composition / Information on Ingredients

Substance: Propyl Acetate
Concentration: Not less than 99 percent
Impurities or Additives: Trace water, possible minor presence of acetic acid and propanol (<1 percent), not considered hazardous at trace concentrations

First Aid Measures

Inhalation: Move to fresh air, keep warm and quiet, seek medical attention if symptoms persist, administer oxygen if breathing is difficult
Skin Contact: Remove contaminated clothing, rinse exposed skin with plenty of water, use soap if skin feels sticky, get medical help for irritation or burns
Eye Contact: Rinse immediately with water for 15-20 minutes, hold eyelids open, remove contact lenses if present and easy to do, get medical attention promptly
Ingestion: Rinse mouth, drink small amounts of water if conscious, never induce vomiting, do not give anything by mouth to an unconscious person, get medical attention

Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical, foam, carbon dioxide, alcohol-resistant foam
Unsuitable Media: Do not use water jets
Specific Hazards: Releases flammable vapors at room temperature, combustion produces carbon monoxide, carbon dioxide, and possible acetic vapors
Protective Equipment for Firefighters: Full protective clothing, self-contained breathing apparatus
Special Procedures: Cool containers exposed to fire, avoid runoff into drains or watercourses

Accidental Release Measures

Personal Precautions: Evacuate unprotected personnel, ventilate area, remove ignition sources, wear chemical-resistant gloves, goggles, and protective clothing
Environmental Precautions: Prevent spillage from reaching drains, sewers, soil, surface water, notify authorities if significant release
Methods for Clean-up: Absorb spill with non-combustible material (sand, earth, vermiculite), collect in containers for disposal, thoroughly ventilate area

Handling and Storage

Safe Handling: Ground and bond containers, use spark-proof tools and explosion-proof equipment, avoid inhalation and skin contact, keep away from food and drinks
Storage Conditions: Store tightly closed in cool, dry, well-ventilated area, keep away from sources of ignition and incompatible materials
Incompatible Substances: Strong oxidizers, acids, alkalis, nitrates
Storage Temperature Limits: Ambient (15-25°C), avoid extreme heat or freezing

Exposure Controls and Personal Protection

Occupational Exposure Limits: ACGIH TLV: 200 ppm, OSHA PEL: 200 ppm (835 mg/m³)
Ventilation: Local exhaust and general ventilation, explosion-proof ventilation recommended
Respiratory Protection: NIOSH-approved air-purifying respirator if vapor concentrations exceed limits
Skin Protection: Impermeable gloves (nitrile, neoprene), lab coat or chemical-resistant clothing
Eye Protection: Safety goggles, face shield recommended for large-scale use
Hygiene Measures: Wash hands before eating, drinking, or smoking, no open flames or smoking, avoid prolonged or repeated exposure

Physical and Chemical Properties

Appearance: Clear, colorless liquid
Odor: Characteristic sweet, fruity
Odor Threshold: 0.042 ppm
pH: Not applicable
Melting Point: -95°C
Boiling Point: 102°C
Flash Point: 14°C (closed cup)
Evaporation Rate: 1.3 (butyl acetate=1)
Flammability: Highly flammable
Upper/Lower Explosive Limits: 7.0% / 1.7% (volume in air)
Vapor Pressure: 22 mm Hg at 20°C
Vapor Density: 3.5 (air=1)
Relative Density: 0.89 (water=1)
Solubility in Water: 1.7 g/100 ml at 20°C
Partition Coefficient (log Kow): 1.2
Auto-Ignition Temperature: 460°C
Decomposition Temperature: Not determined
Viscosity: 0.7 mPa·s at 20°C

Stability and Reactivity

Chemical Stability: Product remains stable in closed containers under recommended storage conditions
Reactivity: Reacts with strong oxidizers, acids, alkalis
Conditions to Avoid: Heat, flames, ignition sources, electrostatic discharge, incompatible materials
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, traces of acetic acid
Polymerization: Will not occur under typical conditions of handling and storage

Toxicological Information

Potential Health Effects: Short-term exposure causes respiratory and eye irritation, dizziness, headache, nausea, long-term and repeated exposure can affect liver and central nervous system
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Toxicity: Oral LD50 (rat): 8700 mg/kg; Dermal LD50 (rabbit): >17720 mg/kg; Inhalation LC50 (rat, 4 hrs): >18,000 ppm
Irritation: Eyes and mucous membranes sensitive on direct contact
Carcinogenicity: No evidence found, not listed by IARC, NTP, OSHA
Mutagenicity: No data available for genetic effects
Other Symptoms: Repeated exposure may cause skin dryness or cracking from defatting properties

Ecological Information

Aquatic Toxicity: Low bioconcentration potential, moderately toxic to aquatic organisms, fish LC50 (Leuciscus idus, 48 hrs): 56 mg/l
Persistence and Degradability: Readily biodegradable under aerobic conditions
Bioaccumulation: Unlikely to accumulate in aquatic organisms
Mobility in Soil: High mobility, potential for leaching into groundwater
Other Adverse Effects: Large quantities may affect water quality by depleting dissolved oxygen, not expected to cause long-term significant environmental harm with responsible use

Disposal Considerations

Waste Treatment Methods: Incinerate in approved facility, do not release into drains, waterways, or soil
Recommended Disposal: Use a licensed chemical disposal contractor, consult local, regional, and national regulations
Contaminated Packaging: Completely drain containers, offer clean containers for recycling or reconditioning, dispose of residues under standard hazardous waste procedures

Transport Information

UN Number: UN1276
UN Proper Shipping Name: Propyl Acetate
Transport Hazard Class: 3 (Flammable liquids)
Packing Group: II
Environmental Hazards: Not classified as environmentally hazardous for transport
Special Precautions: Keep away from heat sources during transport, ensure container integrity, proper EPA registration and documentation
Transportation Labeling: Flammable liquid symbol

Regulatory Information

US TSCA: Listed
Canadian DSL: Listed
EU REACH: Registered
OSHA: Hazardous chemical according to OSHA Hazard Communication Standard
SARA Title III (Section 313): Not subject
California Proposition 65: Not listed
WHMIS Classification: B2 (Flammable liquid), D2B (Toxic material causing other effects)
Other Regulations: Check local, state, and country-specific chemical safety, storage, and disposal guidelines before handling